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　　困苦的爹，辛劳的妈，破烂的院子，破碎的他。西虹市做大做强的路上怎么把老马家落下了？！
　　“汤里没油，兜里没子”的马成钢（沈腾 饰）和春兰（马丽 饰），赶驴打工，家徒四壁，而儿子马继业（肖帛辰 饰）则是他们逆天改命的唯一希望。小马很争气，年年好成绩，一点不娇气，意志贼坚毅。但随着小马一天天长大，他却逐渐发现身边的人们都越来越不对劲……

　　蟹堡王毗邻本店的二号店即将开张了！海绵宝宝满心期待，以为分店经理一职非自己莫属，然而蟹老板却以他不够成熟为理由，将分店交给章鱼哥打理。同时看着蟹堡王做大的痞老板再出毒计，他偷走了海王星国王的王冠，并嫁祸蟹老板，盛怒的海王星要处死蟹老板，但为了拿回王冠，给忠诚的海绵宝宝和派大星六天时间，让他们去无人能够生还的贝壳城取回王冠。而痞老板得逞后偷走了蟹老板的蟹黄堡配方，生意迅速大热，他趁机把能够操纵思想的头盔赠送给顾客们，要通过控制海洋生物称霸世界。另一面，海绵宝宝和派大星踏上了无厘头又凶险万分的寻冠之路，前往传说中独眼巨人栖息的贝壳城……

　　Novelist Larry Donner (Billy Crystal) struggles with writer's block due to his resentment towards his ex-wife Margaret (Kate Mulgrew), who stole his book and garnered mainstream success and critical acclaim with it. Owen Lift (Danny DeVito) is a timid, middle-aged man who still lives with his overbearing, abusive mother (Anne Ramsey). Owen fantasizes of killing his mother but can't summon the courage to bring his desires into fruition. As a student in Larry's community college writing class, Owen is given advice by Larry to view an Alfred Hitchcock film to gain some insight into plot development. He sees Strangers on a Train, in which two strangers conspire to commit a murder for each other, figuring their lack of connection to the victim will, in theory, establish a perfect alibi. Having overheard Larry's public rant that he wish his ex-wife dead, Owen forms a plan to kill Margaret, believing that Larry will respond by killing his mother.
　　He tracks Margaret down to Hawaii and follows her onto a cruise ship, apparently pushing her overboard while she tries to retrieve an earring that fell out. Owen returns from Hawaii to tell Larry of Margaret's death and that Larry now "owes" him the murder of his mother, lest he inform the police Larry was the killer. After having spent the night drinking alone during the hours of Margaret's disappearance, Larry panics because he lacks a sufficient alibi. That, along with a news report announcing the police suspect foul play, convinces Larry he's the prime suspect. He decides to stay with Owen and his mother in an attempt to hide from the police. Larry meets Mrs. Lift, but despite her harsh treatment of him he refuses to kill her. Eventually, when Mrs. Lift drives Owen to the breaking point, Larry finally relents and agrees to go through with the murder.
　　After two unsuccessful attempts, Larry flees the Lift home when Mrs. Lift recognizes him as a suspect from a news broadcast about his ex-wife's disappearance. He boards a train to Mexico and, surprisingly, Owen and Mrs. Lift come along so as to avoid having to lie for him. During the journey, Larry's patience with Mrs. Lift reaches its pinnacle when she impolitely gives him advice on writing. He follows her to the caboose with the intent of throwing her from the train, but stops short when she almost falls off on her own. Owen begins having second thoughts about having his mother killed and comes to help Larry rescue her. Mrs. Lift is grateful at her son for saving her, but unappreciative of Larry's help and kicks him, resulting in him losing his balance, landing on the tracks, and breaking his leg.
　　During his recovery in the hospital, Larry discovers Margaret is still alive; she simply fell overboard by accident and was rescued by a Polynesian fisherman whom she has decided to marry. Much to his annoyance, Larry learns Margaret plans to sell the rights of her ordeal for $1.5 million dollars. On the advice of a fellow patient, Larry chooses to free himself of his obsession with his ex-wife and instead focus on his own life, thereby freeing him of his writer's block.
　　A year later, Larry has finished a novel based on his experiences with Owen and Mrs. Lift entitled Throw Momma from the Train. Owen visits and informs him that his mother has died (of natural causes) and that he's going to New York City for the release of his own book. Unfortunately, Owen reveals his book is also about their experiences together. Thinking his book has been scooped, an enraged Larry proceeds to strangle him, but stops when Owen shows him the book is a children's pop-up book called, Momma, Owen, and Owen's Friend Larry with the story drastically altered to be suitable for children. Months later, Larry, Owen, and Larry's girlfriend Beth (Kim Greist) vacation together in Hawaii, reflecting on the final chapter of Larry's book. Larry and Owen's books have now become best-sellers, making them both successful writers as well as close friends.

　　尼加拉瓜大瀑布，一段离奇惊险的蜜月之旅。刚结婚不久的新郎赛拉斯·帕克（詹姆斯·弗兰科 James Franco饰）与新娘卡蜜儿·福斯特（西耶娜·米勒 Sienna Miller饰）踏上了这次危情冒险之旅。脾气阴晴不定的赛拉斯是个刚刚被假释的小偷，而活泼单纯的卡蜜儿正是他保释官的侄女。赛拉斯一心只想利用这次蜜月之旅逃往加拿大，卡蜜儿则坚信这次尼加拉瓜瀑布之旅，能够彻底改变赛拉斯。
　　然而一场突如其来的车祸，瞬间夺去了卡蜜儿的生命。当赛拉斯前去报警时，却惊奇的发现卡蜜儿起死回生。随后更发生了一连串不可思议的离奇事件。

　　The young daughter of a politician runs away due to lack of attention. She hides in the car of two not too bright crooks who are slowly converted into parent figures as the police web closes down on the supposed kidnappers.

　　电话收单业务主管陶德（Josh Hamilton 饰）惊闻公司要将电话收单外包，相同的工作交由印度职员完成，实在可以节省不少成本。陶德被公司借鸡下蛋派往印度培训当地接班人。苦于工作未满年限陶德只得服从安排。
　　甫下飞机，陶德便目睹印度邋遢又充满活力的异域特色，除了名字被念做托德（蟾蜍）以外似乎没有太大不妥，前来接站的接班人普洛的名片上赫然写着“未来经理”。陶德入住一家私人旅馆，同时经过战场般的荷丽节洗礼，得以更加亲近印度文化。另一方面，陶德为提高工作效率在培训之外适度奖励，收效明显。随着印度部门业绩提升，陶德离开的时候快到了，但他实在不愿让与下属亚莎的爱情成为一段回忆……

　　南California 的West High Sharks高中的Carson决定使出浑身解数带领她团队里的姑娘们赢得全美拉拉队冠军，可是New Yorker 的brooke可不这么想，她比Carson还要坚定冠军属于她们，到底鹿死谁手我们拭目以待..

　　约翰•塔克（杰西•麦特卡尔菲 饰）是学校里面的风头人物，深受女孩子的欢迎，他也乐在其中。不久，他的三位美丽的女友嘉丽、希瑟、贝丝发现了自己的男友都是约翰。感到晴天霹雳的三人决定一争到底，但最后都躲不过被约翰抛弃的命运。
　　本是敌人的她们伤心过后决定联合起来一起对付约翰，惩罚他的花心之举。可是她们的计划在约翰身上并不奏效。这时善良单纯的凯特（布兰特妮•斯诺 饰）成为了她们报复约翰的工具，凯特虽然心里不太愿意，因为她需要诱惑约翰，之后再让他品尝失恋之苦。可是她也希望能走进三位校花的生活圈子中，便同意了。果然，约翰对打扮后美得不可方物的凯特动心不已，竟变了个人似的对凯特的感情专一认真。凯特本来想自己的任务即将完成，可是却发现自己真的爱上了约翰……

　　三名劫匪计划周的去抢劫银行，其中一名化妆成小丑，在银行即将打烊之际潜入，并持枪劫持十多名人质，闻讯赶到的警方，将银行层层包围，试图与劫匪谈判，释放人质，而一阵忙乱之际，劫匪小丑竟离奇消失，甚至挟走百万巨款脱逃出了警方层层包围，但是纽约拥挤街道，忙碌的人潮，多样性的文化，使得他们逃亡的过程中产生种种的笑话，

　　怀揣着对未来的无尽憧憬，年轻的世珍（郑有美 饰）背井离乡千里迢迢的来到了繁华的大都市首尔，在那里，她即将展开新的工作生活。可是，现实并不如想象的那样美好，在拮据的生活条件下，世珍不得不蜗居在一间位于地下室的简陋小房子里。然而，即便是这样，世珍也依然抱着积极乐观的态度过着每一天，唯一让她感到困扰的，是住在隔壁的那个粗犷凶恶的男子。
　　男子名叫吴东哲（朴重勋 饰），曾经混迹于黑社会的他为了替老大顶罪而锒铛入狱，虽说如今已经重获自由，可是身心俱疲的他却再也找不到曾经的那股冲劲了。就是这样的一对毗邻的男女，两人之间不断的产生着误会和笑话，但在渐渐熟悉的过程中，世珍发现了吴东哲那颗已经落灰的真挚和善良的内心，一股清新温暖的感情渐渐的萦绕在了两人的心头。

　　老板司机董大宝偶得祖传古董洗脸盆，身价水涨船高，随之而来的诱惑与考验也更多。在经历了一系列失而复得的闹剧同时，董大宝也收获了比财富更为重要的东西。

　　孤儿钟馗从小立志成为一名捉妖师，却遭到村民们的耻笑羞辱，不得不放弃梦想。长大后的钟馗自称“捉妖大师”，和忽男忽女的鲛人小鱼、憨憨傻傻的人参精欢喜组成“捉妖小分队”，通过装神弄鬼骗钱谋生。 当三人来到洛城，打算继续行骗时，却惊讶的发现真的有妖作乱。一时间，小鱼、欢喜，以及整个洛城的百姓都接连陷入危机。钟馗必须找回自己最初的梦想，获得一个捉妖师真正的力量，才能铲除恶妖，拯救所有人。 钟馗最终打败恶妖，成为了一名合格的捉妖师。接下来，他将带领自己的“捉妖小分队”，继续冒险之旅。